Different Pathogenicity of Duck Hepatitis A Virus 1 Between Pancreatitis-type and Classical Duckling
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摘要: 为明确胰腺型鸭1型甲肝病毒 (DHAV-1) 和经典型DHAV-1对不同品种雏鸭的致病性, 以胰腺型DHAV-1和经典型DHAV-1分别感染7、14、21、28、35d番鸭、半番鸭、樱桃谷鸭和麻鸭, 结果表明番鸭对胰腺型DHAV-1最易感, 半番鸭和樱桃谷鸭次之, 麻鸭最不易感;而樱桃谷鸭对经典型DHAV-1最易感, 番鸭次之;感染胰腺型DHAV-1的番鸭、半番鸭胰腺出血、明显发黄, 肝脏未见出血。表明胰腺型鸭1型甲肝病毒、经典DHAV-1在易感宿主、组织嗜性和特征肉眼病变上均存在明显差异。Abstract: A duck hepatitis A virus 1 (DHAV-1) , designated pancreatitis-type DHAV-1, has been isolated from Muscovy ducklings with yellow or hemorrhagic pancreas.To elucidate different pathogenicity of DHAV-1infection between pancreatitis-type and classical ducklings, Muscovy duck, mallard duck, Cherry valley duck and Maya duck, raised for 7, 14, 21, 28and 35drespectively, were inoculated with pancreatitis-type and classical DHAV-1.The results showed that Muscovy duck was the most sensitive to pancreatitis-type DHAV-1, followed by mallard duck and Cherry valley duck, and the Maya duck was the lowest.However, Cherry valley duck was the most sensitive to classical DHAV-1, followed by Muscovy ducks.Hemorrhagic and yellow pancreas was detected in Muscovy duckling and mallard duckling infected with pancreatitis-type DHAV-1, but no hemorrhage in liver.The above indicated that there were obviously different pathogenicity between pancreatitis-type and classical DHAV-1in sensitive host, and gross lesions.
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Key words:
- Duck Hepatitis A Virus type 1 /
- pancreatitis-type /
- pathogenicity
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