摘要:
为评价鱿鱼MUCIN型糖蛋白的抗疲劳作用,分别以不同剂量的鱿鱼MUCIN型糖蛋白经口给予昆明小鼠连续灌胃4周,研究鱿鱼MUCIN型糖蛋白对小鼠负重力竭游泳时间,肝糖原(LC)、血糖(GLU)、血乳酸(LD)含量和血乳酸脱氢酶(LDH)活性等反映疲劳的生化指标的影响。结果表明,与对照组相比,中、高剂量组能明显延长小鼠力竭游泳时间;增加运动后小鼠LC的储备量和GLU含量,增强LDH的活性,降低LD的含量,减少乳酸在肌肉及血液中的堆积,延缓疲劳的发生。说明鱿鱼MUCIN型糖蛋白对小鼠具有较好的抗疲劳作用。
Abstract:
To evaluate the anti-fatigue effect of mucin glycoprotein from squid,male mice were divided into 4groups randomly and were given different dose of mucin glycoprotein from squid.After 4weeks,the mice′s exhaustive loaded swimming time,liver glycogen level,glucose level,blood lactic acid level,and lactic acid dehydrogenase activity were detected.Compared with the control group,medium and high dose of squid mucin glycoprotein could significantly prolong mice′s exhaustive loaded-swimming time,increase the content of liver glycogen and glucose, improve the blood lactate dehydrogenase activity,while reduce the after-exercise blood lactic acid content,which would prevent the accumulation of lactic acid in muscle and blood,so as to postpone the occurrence of fatigue.In conclusion,Mucin glycoprotein from squid had obvious anti-fatigue effect on mice.
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