鸭坦布苏病毒感染对鸭T淋巴细胞转化功能的影响

陈翠腾; 苏荣茂; 黄瑜; 傅光华; 程龙飞; 陈红梅; 万春和; 傅秋玲; 施少华; 林建生

doi:10.19303/j.issn.1008-0384.2014.11.003

鸭坦布苏病毒感染对鸭T淋巴细胞转化功能的影响

doi: 10.19303/j.issn.1008-0384.2014.11.003

1. 福建省农业科学院畜牧兽医研究所,福建福州,350013;
2. 福建省畜牧兽医总站,福建福州,350003

基金项目:

国家自然科学基金项目 (31201936)

国家现代农业产业技术体系建设专项 (CARS-43)

福建省种业创新与产业化工程项目 (2014)

详细信息

作者简介:
陈翠腾 (1987-) , 女, 硕士, 主要从事动物病原与分子生物学研究 (E-mail:973900245@qq.com);黄瑜 (1965-) , 男, 博士, 研究员, 主要从事家禽传染病研究 (E-mail:huangyu_815@163.com)

中图分类号: S858.32
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- 被引次数: 0
出版历程
- 收稿日期: 2014-08-22
- 刊出日期: 2014-11-18

Effect of Duck Infected with Duck Tembusu Virus on T Lymphocyte Function

1. Institute of Animal Husbandry and Veterinary Medicine,Fujian Academy of Agricultural Sciences;
2. Fujian General Station of Animal Husbandry and Veterinary

摘要

摘要: 以麻鸭为动物模型, 测定鸭坦布苏病毒感染后鸭的T淋巴细胞增殖转化能力。结果显示鸭坦布苏病毒感染的试验组鸭外周血淋巴细胞刺激指数呈先上升后下降再回升的趋势, 其中于第3d试验组淋巴细胞刺激指数极显著高于对照组 (P<0.01) , 于第5d下降至对照组水平, 于第7、15d显著低于对照组 (P<0.05) , 于第21d回升至接近对照组水平。以上结果表明, 鸭坦布苏病毒感染鸭后7²1d会抑制鸭T淋巴细胞的增殖转化功能, 造成鸭T淋巴细胞的免疫抑制。
- 鸭坦布苏病毒 /
- 淋巴细胞增殖 /
- 刺激指数
Abstract: In this study, Sheldrake was used as the animal model, and we tested the proliferation of its T lymphocyte after infected by duck Tembusu virus.The result showed that after duck Tembusu virus infection, stimulation index of peripheral blood lymphocyte of test group increased first and then decreased, and recovered again.Lymphocyte stimulation index of test group was significantly (P<0.01) higher than that of control group at3dpi (day post-infected) , and then decreased to the level of control group at 5dpi, and was significantly lower (P<0.05) than that of control group at 7dpi and 15 dpi, and then recovered to the level of control group at 21 dpi.The result indicated that duck Tembusu virus infection could cause the duck T lymphocyte immune suppression during 7dpi to 21 dpi.
- duck Tembusu virus /
- lymphocyte proliferation /
- stimulation index

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参考文献(14)

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