The Active Efflux of Riemerella Anatipestifer for Fluoroquinolone Antibiotics

JIN Long-xiang; CHENG Long-fei; CHEN Hong-mei; PAN Yi-zhe; HUANG Yu

doi:10.19303/j.issn.1008-0384.2014.05.002

Volume 29 Issue 5

May 2014

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Article Navigation > Fujian Journal of Agricultural Sciences > 2014 > 29(5): 413-416

JIN Long-xiang, CHENG Long-fei, CHEN Hong-mei, PAN Yi-zhe, HUANG Yu. The Active Efflux of Riemerella Anatipestifer for Fluoroquinolone Antibiotics[J]. Fujian Journal of Agricultural Sciences, 2014, 29(5): 413-416. doi: 10.19303/j.issn.1008-0384.2014.05.002

Citation:

JIN Long-xiang, CHENG Long-fei, CHEN Hong-mei, PAN Yi-zhe, HUANG Yu. The Active Efflux of Riemerella Anatipestifer for Fluoroquinolone Antibiotics[J]. Fujian Journal of Agricultural Sciences, 2014, 29(5): 413-416. doi: 10.19303/j.issn.1008-0384.2014.05.002

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The Active Efflux of Riemerella Anatipestifer for Fluoroquinolone Antibiotics

doi: 10.19303/j.issn.1008-0384.2014.05.002

1. Institute of Animal Husbandry and Veterinary Medicine,Fujian Academy of Agricultural Sciences;
2. Animal Science College of Jiangxi Agriculture University

Received Date: 2014-02-19
Publish Date: 2014-05-18

Abstract

Abstract

To study the active efflux mechanism of Riemerella anatipestifer for fluoroquinolone antibiotics (FQNS) such as norfloxacin, enrofloxacin, ciprofloxacin, ofloxacin and levofloxacin, the minimum inhibitory concentration (MIC) of 25 Riemerella anatipestifer isolates for FQNS was tested, and simultaneously the MIC was detected after adding carbonylcyanide-m-chlorophenylhydrazone (CCCP) .The ratios of the FQNS-resistant strains were 84%, 72%, 76%, 68%and 36%;76%of strains were resistant to two or more drugs.CCCP increased the sensitivity of the drug-resistant bacteria to FQNS (except levofloxacin) , indicating that active efflux mechanism played an important role in resistance mechanisms to FQNS in Riemerella anatipestifer.
- Riemerella anatipestifer,
- fluoroquinolone antibiotics,
- the active efflux,
- the minimum inhibitory concentration

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References(12)

References

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