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Volume 34 Issue 11
Nov.  2019
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Article Contents
TAO Y, LU J H, REN S M. Polymorphism of IGFBP2 Gene Relating to Meat Quality of Sujiang Pigs [J]. Fujian Journal of Agricultural Sciences,2019,34(11):1283−1287. doi: 10.19303/j.issn.1008-0384.2019.11.007
Citation: TAO Y, LU J H, REN S M. Polymorphism of IGFBP2 Gene Relating to Meat Quality of Sujiang Pigs [J]. Fujian Journal of Agricultural Sciences,2019,34(11):1283−1287. doi: 10.19303/j.issn.1008-0384.2019.11.007

Polymorphism of IGFBP2 Gene Relating to Meat Quality of Sujiang Pigs

doi: 10.19303/j.issn.1008-0384.2019.11.007
  • Received Date: 2019-06-26
  • Rev Recd Date: 2019-09-04
  • Publish Date: 2019-11-01
  •   Objective  Genetic variation of the insulin-like growth factor binding protein 2 gene (IGFBP2 gene), relating to the meat quality of Sujiang pigs was studied.  Method  The polymorphism of IGFBP2 gene was detected by PCR-RFLP in Sujiang pigs, Jiangquhai pigs and Duroc pigs, and the association between IGFBP2 gene polymorphism and meat quality traits in Sujiang pigs was analyzed.  Result  One common Msp Ⅰ polymorphism in the intron 2 of IGFBP2 gene was found in the 3 pig populations. It consisted of 3 genotypes (AA, AB and BB) and two alleles (A and B) with AB being the dominant genotype and B the prevailing allele. The polymorphisms of the genes from the 3 pig species were moderate on their information content. The meat marbling of Sujiang pigs with the AA and AB genotypes was significantly more than that with the BB genotypes ( P< 0.05). The meat color of the pigs with the AA genotype was significantly more intense than that with the AB and BB genotypes ( P<0.05).  Conclusion  The PCR-RFLP- Msp I polymorphism in the intron 2 of IGFBP2 gene of Sujiang pigs appeared to significantly correlate with the marbling and color of the pork. Consequently, the gene could potentially be used to study the meat quality improvement through breeding.
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  • [1]
    SLOOTWEG M C, OHLSSON C, SALLES J P, et al. Insulin-like growth factor binding proteins-2 and-3 stimulate growth hormone receptor binding and mitogenesis in rat osteosarcoma cells [J]. Endocrinology, 1995, 136(10): 4210−4217. doi: 10.1210/endo.136.10.7545101
    [2]
    RAJARAM S, BAYLINK D J, MOHAN S. Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions [J]. Endocrine Reviews, 1997, 18(6): 801−831.
    [3]
    ROSS M, FRANCIS G L, SZABO L, et al. Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not Des-(1-3)-IGF-1 [J]. Biochemical Journal, 1989, 258(1): 267−272. doi: 10.1042/bj2580267
    [4]
    杨华, 徐珍, 左波. 猪IGFBP2基因多态性及其与胴体、肉质性状的关联分析 [J]. 中国畜牧杂志, 2017, 53(3):25−28.

    YANG H, XU Z, ZUO B. Polymorphism of IGFBP2 Gene and Its Association with Carcass and Meat Quality Traits in Pigs [J]. Chinese Journal of Animal Science, 2017, 53(3): 25−28.(in Chinese)
    [5]
    ROHRER G A, THALLMAN R M, SHACKELFORD S, et al. A genome scan for loci affecting pork quality in a Duroc-Landrace F2 population [J]. Animal Genetics, 2006, 37(1): 17−27. doi: 10.1111/j.1365-2052.2005.01368.x
    [6]
    PRASONGSOOK S, CHOI I, BATES R O, et al. Association of insulin-like growth factor binding protein 2 genotypes with growth, carcass and meat quality traits in pigs [J]. Journal of Animal Science and Technology, 2015, 57: 31. doi: 10.1186/s40781-015-0063-3
    [7]
    倪黎纲, 赵旭庭, 周春宝, 等. 苏姜猪世代选育中生长、胴体和肉质性能的测定分析 [J]. 畜牧与兽医, 2015, 47(1):45−47.

    NI L G, ZHAO X T, ZHOU C B, et al. Determination and analysis of growth, carcass and meat quality in Sujiang pig during the generation selection [J]. Animal Husbandry & Veterinary Medicine, 2015, 47(1): 45−47.(in Chinese)
    [8]
    周根来, 赵旭庭, 陶勇, 等. 饲粮中消化能、粗蛋白质和粗纤维水平对育肥苏姜猪生长性能、胴体性状和肉品质的影响 [J]. 动物营养学报, 2018, 30(8):3293−3301. doi: 10.3969/j.issn.1006-267x.2018.08.049

    ZHOU G L, ZHAO X T, TAO Y, et al. Effects of dietary digestible energy, crude protein and crude fiber levels on growth performance, carcass traits and meat quality of fattening Sujiang pigs [J]. Chinese Journal of Animal Nutrition, 2018, 30(8): 3293−3301.(in Chinese) doi: 10.3969/j.issn.1006-267x.2018.08.049
    [9]
    刘海霞, 朱爱文. 猪IGFBP2基因遗传多态性及其与肉质性状的关联分析 [J]. 中国畜牧兽医, 2017, 44(10):3016−3022.

    LIU H X, ZHU A W. Polymorphism of IGFBP2 Gene and Its Association with Meat Quality Traits in Pigs [J]. China Animal Husbandry & Veterinary Medicine, 2017, 44(10): 3016−3022.(in Chinese)
    [10]
    王新亮. IGFBP2通过ERK1/2信号通路调控RA-FLS细胞生物学行为机制研究[D]. 广州: 暨南大学, 2017.

    WANG X L. The role of IGFBP2 through ERK1/2 signal pathways regulating the RA-FLS cell biology behavior[D]. Guangzhou: Jinan University, 2017. (in Chinese)
    [11]
    何涛, 和姬苓. IGFBP-2结构功能与肿瘤关系研究进展 [J]. 西部医学, 2008, 20(4):858−860. doi: 10.3969/j.issn.1672-3511.2008.04.094

    HE T, HE J L. Research progress in the relationship between the structure and function of IGFBP-2 and cancer [J]. Medical Journal of West China, 2008, 20(4): 858−860.(in Chinese) doi: 10.3969/j.issn.1672-3511.2008.04.094
    [12]
    许淑芬, 刘磊, 方艳秋, 等. IGFBP-2在卵巢肿瘤组织中的表达及临床意义 [J]. 中国妇幼保健, 2013, 28(27):4537−4539. doi: 10.7620/zgfybj.j.issn.1001-4411.2013.27.40

    XU S F, LIU L, FANG Y Q, et al. Expression and clinical significance of IGFBP-2 in ovarian Tumor tissue [J]. Maternal and Child Health Care of China, 2013, 28(27): 4537−4539.(in Chinese) doi: 10.7620/zgfybj.j.issn.1001-4411.2013.27.40
    [13]
    ZHAO X H, LI M Y, XU S S, et al. Single Nucleotide Polymorphisms in IGFBP-2 Gene and Their Associations with Body Weight Traits on Jinghai Yellow Chicken [J]. Revista Brasileira De Ciência Avícola, 2015, 17(4): 497−502. doi: 10.1590/1516-635X1704497-502
    [14]
    WANG W J, MENG Q Y, HU X X, et al. Chromosome location and association of haplotypes of insulin-like growth factor binding protein-2 with production performance in swine [J]. Biochemical Genetics, 2008, 46(7-8): 381−391. doi: 10.1007/s10528-007-9128-4
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