Acute Toxicities of Six Aquaculture Drugs on Juvenile Opsariichthys bidens

  Objective   Acute toxicities of 6 aquaculture drugs on juvenile Opsariichthys bidens were determined for safe applications.

  Method   Medicine toxicity accumulation coefficients (MACs) of 6 drugs commonly applied for aquaculture were determined on the fish in a tank at a controlled temperature of 25.8–28.3 ℃.

  Result   The drugs at specific doses displayed varied degrees of safety that ranked as Meiting Ⅱ (2.222 mg·L⁻¹)＞Chelunchongbike (0.790 mg·L⁻¹)＞povidone iodine (0.659 mg·L⁻¹)＞Baitexindilin (0.225 mg·L⁻¹)＞Baitezhihuandi (0.214 mg·L⁻¹)＞Baidianjing (0.006 mg·L⁻¹). The MACs of these drugs on O. bidens were positive but differed in the toxic effect to the fish due to differentiated accumulation and degradation of as well as sensitivity of the fish to the individual drugs.

  Conclusion   According to the classification standards, Meiting Ⅱ was determined to be low toxic, while Chelunchongbike, povidone iodine, Baitexindilin, and Baitezhihuandi, moderately toxic, and Baidianjing, highly toxic to O. bidens juveniles.